منابع مشابه
Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection.
A 13-month-old male presented with repetitive episodes of myoclonic jerks of the head and extremities for two months. His past medical history revealed that his non-immunized mother had measles at the time of delivery. Measles antibody titers in serum and cerebrospinal fluid (CSF) were 1/512 (hemagglutinin inhibition [HI]) and 1/128 HI, respectively. Immunofixation electrophoresis of CSF reveal...
متن کاملExpression of measles virus RNA in peripheral blood mononuclear cells of patients with measles, SSPE, and autoimmune diseases.
In order to characterize measles virus (MV) infection in peripheral blood mononuclear cells (PBMCs), RNA was isolated from PBMCs after PHA-stimulation for 72 hr of 9 patients with acute measles, 16 patients with subacute sclerosing panencephalitis (SSPE), 13 patients with various autoimmune diseases, and 16 healthy control donors. The RNA obtained was screened for the presence of MV N (nucleoca...
متن کاملReview of the effect of measles vaccination on the epidemiology of SSPE.
BACKGROUND When measles vaccines were widely introduced in the 1970s, there were concerns that they might cause subacute sclerosing panencephalitis (SSPE): a very rare, late-onset, neurological complication of natural measles infection. Therefore, SSPE registries and routine measles immunization were established in many countries concurrently. We conducted a comprehensive review of the impact o...
متن کاملIncreased positive selection pressure in persistent (SSPE) versus acute measles virus infections.
We compared the extent of positive selection acting on acute and persistent strains of measles virus (MV). Far stronger positive selection was found in the fusion (F) and haemagglutinin (H) genes from subacute sclerosing panencephalitis (SSPE) compared to acute MV cases. Most of the positively selected sites identified in these surface glycoprotein genes from SSPE cases correspond to structural...
متن کاملBlocking Factors in Sspe Patients
Since the description of a case with "diffuse encephalitis with sclerosing inflammation of the hemisphere white matter" by Bodechtel and Guttman (1), there have been numerous reports that have indicated that measles virus is associated with this disease. Subacute sclerosing panencephalitis (SSPE) I occurs mostly in children and young adults as a slow progressive inflammatory disorder of the cen...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1999
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-13-2-3